Background:This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
仕様
Synonyms:CR6,Cytokine responsive protein CR6,Cytokine-responsive protein CR6,DDIT-2,DDIT2,DNA damage-inducible transcript 2 protein,GA45G,Gadd45g,Growth arrest and DNA damage inducible gamma,Growth arrest and DNA damage-inducible protein GADD45 gamma,GRP17
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from the C-terminal region of human GADD 45gamma
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Dilution:WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Gene_ID(human):10912
Swissprot:O95257
Isotype:IgG
Research Areas:Cell Biology, Epigenetics and Nuclear Signaling