Background：Gamma-aminobutyric acid （GABA） is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA（A/C）] receptors, to produce fast synaptic inhibition, and metabotropic [GABA（B）] receptors, to produce slow, prolonged inhibitory signals. The GABA（B） receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA（B） receptor 1 and GABA（B） receptor 2. The GABA（B） receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants.
仕様
Synonyms：dJ271M21.1.1,dJ271M21.1.2,FLJ92613,GABA-B receptor 1,GABA-B-R1,GABA-BR1,GABAB R1,GABAB subunit 1c,GABABR1,GABBR1 3,GABBR1,GABR1,Gamma aminobutyric acid （GABA） B receptor 1,Gamma-aminobutyric acid type B receptor subunit 1,Gb1,GPRC3A,Seven transmembrane helix receptor
Host：Rabbit
Reactivity：Human,Mouse,Rat,Monkey
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the C-terminal region of human GABAB R1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
