Background：This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM （warts, hypogammaglobulinemia, infections, and myelokathexis） syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仕様
Synonyms：C-X-C chemokine receptor type 4,CD184,CD184 antigen,Chemokine （C X C motif） receptor 4,Chemokine CXC Motif Receptor 4,CXC-R4,CXCR-4,CXCR4,CXCR4,D2S201E,FB22,Fusin,HM89,HSY3RR,LAP 3,LAP3,LCR1,LESTR,Leukocyte derived seven transmembrane domain receptor,Leukocyte-derived seven transmembrane domain receptor,Lipopolysaccharide associated protein 3,Neuropeptide Y receptor Y3,NPY3R,NPYR,NPYRL,NPYY3,NPYY3R,Probable G protein coupled receptor lcr1 homolog,SDF 1 receptor,SDF-1 receptor,SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR,Stromal cell derived factor 1 receptor,Stromal cell-derived factor 1 receptor,WHIM,WHIMS
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the C-terminal region of human Fusin
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IF 1：100-1：300, ELISA 1：40000
Gene_ID（human）：7852
Swissprot：P61073
Isotype：IgG
Research Areas：Cancer, Metabolism, Immunology, Microbiology, Neuroscience, Stem cells
