Background:Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'.
仕様
Synonyms:AF6q21,AF6q21 protein,DKFZp781A0677,FKHR2,FKHRL 1,FKHRL1,FKHRL1P2,Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1,Forkhead box O3,Forkhead box O3A,Forkhead box protein O3,Forkhead box protein O3A,Forkhead Drosophila homolog of in rhabdomyosarcoma like 1,Forkhead homolog (rhabdomyosarcoma) like 1,Forkhead in rhabdomyosarcoma like 1,Forkhead in rhabdomyosarcoma-like 1,FOX O3A,FOXO2,foxo3,FOXO3,FOXO3A,MGC12739,MGC31925
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human FoxO3A around the non-phosphorylation site of Ser253.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Dilution:WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Gene_ID(human):2309
Swissprot:O43524
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling