Background：The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha （ER-alpha）, in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
仕様
Synonyms：[Acyl-carrier-protein] S acetyltransferase,[Acyl-carrier-protein] S malonyltransferase,3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase,3-oxoacyl-[acyl-carrier-protein] reductase,3-oxoacyl-[acyl-carrier-protein] synthase,Enoyl-[acyl-carrier-protein] reductase,FAS,FAS,FASN,Fatty acid synthase,MGC14367,MGC15706,OA 519,Oleoyl-[acyl-carrier-protein] hydrolase,SDR27X1,Short chain dehydrogenase/reductase family 27X member 1
Host：Rabbit
Reactivity：Human
Applications：WB,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the Internal region of human Fatty Acid Synthase.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, ELISA 1：10000
Gene_ID（human）：2194
Swissprot：P49327
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
