Background:Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4).
仕様
Synonyms:ERK 1,ERK,ERK-1,ERK1,ERT 2,ERT2,Extracellular Signal Regulated Kinase 1,Extracellular signal related kinase 1,Extracellular signal-regulated kinase 1,HGNC6877,HS44KDAP,HUMKER1A,Insulin Stimulated MAP2 Kinase,Insulin-stimulated MAP2 kinase,MAP kinase 1,MAP kinase 3,MAP Kinase,MAP kinase isoform p44,MAPK 1,MAPK 3,MAPK,MAPK1,Mapk3,MGC20180,Microtubule Associated Protein 2 Kinase,Microtubule-associated protein 2 kinase,Mitogen Activated Protein Kinase 3,Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 3,MK03,OTTHUMP00000174538,OTTHUMP00000174541,p44 ERK1,p44 MAPK,p44-ERK1,p44-MAPK,P44ERK1,P44MAPK,PRKM 3,PRKM3,Protein Kinase Mitogen Activated 3
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IF,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from the Internal region of human ERK 1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Dilution:WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:40000
Gene_ID(human):5595
Swissprot:P27361
Isotype:IgG
Research Areas:Cancer, Neuroscience, Signal transduction, Stem cells