Background：This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 （RTEL1）, generates a non-coding transcript.TNFRSF6B （TNF Receptor Superfamily Member 6b） is a Protein Coding gene. Diseases associated with TNFRSF6B include Bladder Urothelial Carcinoma and Oral Cavity Cancer. Among its related pathways are Apoptosis and Autophagy and Innate Immune System. GO annotations related to this gene include receptor activity. An important paralog of this gene is TNFRSF11B.
仕様
Synonyms：DcR3,Decoy receptor 3,Decoy receptor for Fas ligand,DJ583P15.1.1,M68,M68E,OTTHUMP00000031583,TNF6B,TNFRSF6B,TR6,Tumor necrosis factor receptor superfamily member 6B,Tumor necrosis factor receptor superfamily member 6b decoy,UNQ186/PRO212
Host：Rabbit
Reactivity：Human
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the C-terminal region of human DcR3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：200-1：1000, ELISA 1：5000
