Background:Protein kinase with a significantly reduced Ca2+/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm.
仕様
Synonyms:CaMK-like CREB regulatory kinase 2,CL2,CLICK-II,CLICK2,DCAMK L2,DCAMKL 2,DCDC 3,DCDC 3B,DCDC3,DCDC3B,DCK 2,DCK2,DCLK 2,Dclk2,DCLK2,DKFZp761I032,Doublecortin and CaM kinase like 2,Doublecortin domain-containing protein 3B,Doublecortin like and CAM kinase like 2,Doublecortin like kinase 2,Doublecortin-like and CAM kinase-like 2,Doublecortin-like kinase 2,MGC45428,Serine/threonine protein kinase DCLK2,Serine/threonine-protein kinase DCLK2
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IF,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from the N-terminal region of human DCAMKL2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Dilution:WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:10000