Background：Cytochrome c oxidase （COX） is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 （neighbor of COX4） gene in a head-to-head orientation, and shares a promoter with it.
仕様
Synonyms：AL024441,COX 4,COX IV 1,COX IV,COX IV-1,Cox4,COX41,Cox4a,COX4B,COX4I1,COX4I2,COX4L2,COXIV,Cytochrome c oxidase polypeptide IV,Cytochrome c oxidase subunit 4 isoform 1 mitochondrial,Cytochrome c oxidase subunit 4 isoform 1,mitochondrial,Cytochrome C Oxidase subunit IV,Cytochrome c oxidase subunit IV isoform 1,Cytochrome c oxidase subunit IV isoform 2 （lung）,Cytochrome c oxydase subunit 4,dJ857M17.2,MGC105470,MGC72016
Host：Rabbit
Reactivity：Human
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the N-terminal region of human COX4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：200-1：1000, ELISA 1：20000
Gene_ID（human）：1327
Swissprot：P13073
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction, Tags ＆ Cell Markers
