Background:This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene
仕様
Synonyms:Androgen withdrawal and apoptosis induced protein RVP1 like,AWAL,BEC 1,BEC1,Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome),Claudin-5,Claudin5,CLD5,CLDN 5,Cldn5,CPETR L1,CPETRL 1,CPETRL1,TMDVCF,TMVCF,Transmembrane protein deleted in VCFS,Transmembrane protein deleted in velocardiofacial syndrome
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from the C-terminal region of human Claudin-5
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Dilution:WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000