Background：This gene encodes a member of the ATP-binding cassette （ABC） transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies （ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White）. This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene.
仕様
Synonyms：ABC 35,ABC35,ABCC 7,ABCC7,ATP binding cassette sub family C member 7,ATP Binding Cassette Superfamily C Member 7,ATP binding cassette transporter sub family C member 7,ATP-binding cassette sub-family C member 7,cAMP dependent chloride channel,cAMP-dependent chloride channel,CF,CFTR,CFTR/MRP,CFTR,Channel conductance controlling ATPase,Channel conductance-controlling ATPase,Cystic fibrosis transmembrane conductance regulator （ATP-binding cassette sub family C,member 7）,Cystic fibrosis transmembrane conductance regulator,Cystic fibrosis transmembrane conductance regulator ATP binding cassette sub family C member 7,Cystic Fibrosis Transmembrane Regulator,dJ760C5.1,MRP 7,MRP7,TNR CFTR
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human CFTR around the non-phosphorylation site of Ser737.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
