Background：Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
仕様
Synonyms：Activator protein 1,AP 1,C FOS,Cellular oncogene c fos,Cellular oncogene fos,FBJ murine osteosarcoma viral （v fos） oncogene homolog （oncogene FOS）,FBJ murine osteosarcoma viral oncogene homolog,FBJ murine osteosarcoma viral v fos oncogene homolog,FBJ Osteosarcoma Virus,FOS,FOS protein,FOS,G0 G1 switch regulatory protein 7,G0/G1 switch regulatory protein 7,G0S7,Oncogene FOS,p55,proto oncogene c Fos,Proto oncogene protein c fos,Proto-oncogene c-Fos,v fos FBJ murine osteosarcoma viral oncogene homolog
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC-p,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human c-Fos around the non-phosphorylation site of Ser362.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
