Background:Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
仕様
Synonyms:Apoptotic protease Mch-2,Apoptotic protease MCH2,CASP-6,CASP6,CASP6,Caspase 6,Caspase 6 apoptosis related cysteine protease,Caspase 6,apoptosis related cysteine peptidase,Caspase-6 subunit p11,Mch2,OTTHUMP00000162742,OTTHUMP00000162743
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human Caspase-6 around the non-phosphorylation site of Ser257.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Dilution:WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Gene_ID(human):839
Swissprot:P55212
Isotype:IgG
Research Areas:Cancer, Cell Biology, Metabolism, Neuroscience