Background:Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
仕様
Synonyms:Apoptosis associated speck like protein containing a CARD,Apoptosis-associated speck-like protein containing a CARD,ASC,ASC,CARD 5,CARD5,Caspase recruitment domain containing protein 5,Caspase recruitment domain protein 5,Caspase recruitment domain-containing protein 5,hASC,MGC10332,PYCARD,PYD and CARD domain containing,PYD and CARD domain containing protein,PYD and CARD domain-containing protein,Target of methylation induced silencing 1,Target of methylation-induced silencing 1,TMS 1,TMS,TMS1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from the N-terminal region of human ASC
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Dilution:WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000