Background：The basic job of aquaporin 2 is to reabsorb water from the urine while its being removed from the blood by the kidney. Aquaporin 2 is in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes, but when it is needed vasopressin binds to the cell surface vasopressin receptor, activating a signaling pathway that causes the aquaporin 2 containing vesicles to fuse with the plasma membrane so the aquaporin 2 can be used by the cell.
仕様
Synonyms：ADH water channel,AQP 2,AQP CD,AQP-2,AQP-CD,AQP2,AQP2,AQPCD,Aquaporin 2 collecting duct,Aquaporin CD,Aquaporin-2,Aquaporin-CD,Aquaporin2,Aquaporine 2,Collecting duct water channel protein,MGC34501,Water channel aquaporin 2,Water channel protein for renal collecting duct,WCH CD,WCH-CD,WCHCD
Host：Rabbit
Reactivity：Human,Mouse,Rat,Monkey
Applications：WB,IHC-p,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from human AQP2 around the non-phosphorylation site of Ser256.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：200-1：1000, ELISA 1：10000
Gene_ID（human）：359
Swissprot：P41181
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
