Background:Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
仕様
Synonyms:Activator protein 1,AP 1,AP1,cJun,Enhancer Binding Protein AP1,Jun Activation Domain Binding Protein,JUN,Jun oncogene,JUN protein,Jun proto oncogene,JUN,JUNC,Oncogene JUN,p39,Proto oncogene c jun,Proto oncogene cJun,Proto-oncogene c-jun,Transcription Factor AP 1,Transcription factor AP-1,Transcription Factor AP1,V jun avian sarcoma virus 17 oncogene homolog,V jun sarcoma virus 17 oncogene homolog (avian),V jun sarcoma virus 17 oncogene homolog,V-jun avian sarcoma virus 17 oncogene homolog,vJun Avian Sarcoma Virus 17 Oncogene Homolog
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF,ELISA
Concentration:1mg/mL
Immunogen:Synthesized peptide derived from human AP-1 around the non-phosphorylation site of Thr91.
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Dilution:WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300, ELISA 1:5000-1:20000
Gene_ID(human):3725
Swissprot:P05412
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal transduction