Background：The protein encoded by this gene, Aldolase A （fructose-bisphosphate aldolase）, is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes （A, B, and C）, encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.
仕様
Synonyms：ALDA,Aldo1,ALDOA,ALDOA,Aldolase 1,Aldolase A,Aldolase A fructose bisphosphatase,Aldolase A fructose bisphosphate,Aldolase,fructose-bisphosphate A,Epididymis secretory sperm binding protein Li 87p,FRUCTOALDOLASE A,Fructose 1 6 bisphosphate triosephosphate lyase,Fructose bisphosphate aldolase A,Fructose bisphosphate aldolase,FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE A,Fructose-bisphosphate aldolase A,Fructose-bisphosphate aldolase A Muscle-type,GSD12,HEL S 87p,Lung cancer antigen NY LU 1,Lung cancer antigen NY-LU-1,MGC10942,MGC17716,MGC17767,Muscle type aldolase,Muscle-type aldolase,RNALDOG5
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IF,ELISA
Concentration：1mg/mL
Immunogen：Synthesized peptide derived from the N-terminal region of human Aldolase A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
Dilution：WB 1：500-1：2000, IF 1：100-1：300, ELISA 1：10000
Gene_ID（human）：226
Swissprot：P04075
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
