86-4062-87 ［取扱停止］Rabbit anti-AIM2 Polyclonal Antibody 20uL RD70746A
[Reddot Biotech] Rabbit anti-AIM2 Polyclonal Antibody 20uL
特徴
- Background：Interferon-inducible protein AIM2 （Absent in melanoma 2） is a 343 amino acid protein belonging to the HIN-200 family. Induced by IFN-©, AIM2 is thought to act as a tumor suppressor by repressing NF˚B transcriptional activity. Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain. The DAPIN domain is composed mostly of a-helixes and is a protein-protein interaction domain capable of binding other DAPIN domains. The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.
仕様
- Synonyms：Absent in melanoma 2,AIM 2,Aim2,AIM2,Interferon-inducible protein AIM2,OTTHUMP00000035296,PYHIN4
- Host：Rabbit
- Reactivity：Human
- Applications：WB,IHC-p,IF,ELISA
- Concentration：1mg/mL
- Immunogen：Synthesized peptide derived from the Internal region of human AIM2
- Purification Method：Affinity purification
- Clonality：Polyclonal
- Conjugation：Unconjugated
- Buffer：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
- Dilution：WB 1：500-1：2000, IHC 1：100-1：300, IF 1：200-1：1000, ELISA 1：40000
- Gene_ID（human）：9447
- Swissprot：O14862
- Isotype：IgG
- Research Areas：Cancer, Epigenetics and Nuclear Signaling
- サイズ：20uL
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