Background：Somatostatin is one of seven known polypeptide hormones produced in the pancreas. It functions as an inhibitory hormone of the neuroendocrine system and is secreted by D cells of the islets of Langerhans, the fundus and antrum of the stomach and in the upper small intestine. The antibody labels somatostatin-containing cells and is a useful aid for classification of pancreatic tumors and islet cell hyperplasia.
