Background：KRT16 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Diseases associated with KRT16 includePachyonychia Congenita 1andPalmoplantar Keratoderma, Nonepidermolytic, Focal. Among its related pathways areCytoskeleton remodeling NeurofilamentsandKeratinization .This antibody reacts with the 48 kDa protein corresponding to cytokeratin 16 and labels cytokeratin 16 present inKeratinized and hyperplastic squamous epithelium which can be used in the diagnosis of squamous cell carcinoma.
仕様
Synonyms：CK 16,CK-16,CK16,Cytokeratin-16,Cytokeratin16,FNEPPK,Focal non epidermolytic palmoplantar keratoderma,K 16,K16,K1C16,K1CP,Keratin 1 type I,Keratin 16,Keratin,Keratin type I cytoskeletal 16,Keratin-16,Keratin16,KRT 16,Krt16,KRT16A,NEPPK,PC1,type I cytoskeletal 16
Host：Mouse
Reactivity：Human
Applications：IHC-p
Concentration：1mg/mL
Immunogen：Full length protein from eukaryotic expression system.
Purification Method：Affinity purification
Clonality：Monoclonal
Clone No.：LE5B1
Conjugation：Unconjugated
Buffer：PBS with 50％ glycerol, 0.5％ BSA and 0.02％ sodium azide.
