Background:CD43 is mainly marked on T cells and expressed in normal T lymphocytes, myeloid cells, macrophages and plasma cells. Normal B cells or reactive B cells are CD43-. Expression of CD43 in various lymphatic hematopoietic tumors is complex. 90% T lymphocytic lymphoma are CD43+, 30% low grade B cell lymphoma are CD43+, 69% B cell acute lymphoblastic leukemia are CD43+, 97% T cell acute lymphoblastic leukemia are CD43+, 44% anaplastic large cell lymphoma are CD43+, all extramedullary myeloma / granulocytic sarcoma are CD43+, and part of myeloma CD43 are positive. It is usually detected combined with other T cell markers such as CD3 and CD45RO for diagnosis of T cell lymphoma.
仕様
Synonyms:CD 43,CD43,CD43 antigen,Galactoglycoprotein,GALGP,GPL 115,GPL115,Human gene for sialophorin,Leucocyte sialoglycoprotein,LEUK,Leukocyte large sialoglycoprotein,Leukocyte sialoglycoprotein,Leukosialin,LSN,Ly-48,sialophorin (gpL115,leukosialin,CD43),Sialophorin,Spn
Host:Mouse
Reactivity:Human
Applications:IHC-p
Concentration:1mg/mL
Immunogen:Full length protein from eukaryotic expression system.
Purification Method:Affinity purification
Clonality:Monoclonal
Clone No.:LE2B1
Conjugation:Unconjugated
Buffer:PBS with 50% glycerol, 0.5% BSA and 0.02% sodium azide.