Background：S100A4 （S100 Calcium Binding Protein A4） is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Diseases associated with S100A4 includeBile Duct AdenocarcinomaandPancreatic Cancer. Among its related pathways areCa, cAMP and Lipid Signaling.
仕様
Synonyms：18A2,42A,calcium Placental protein,Calvasculin,CAPL,Fibroblast specific protein 1 （FSP1）,Fibroblast specific protein 1,Fibroblast specific protein,FSP1,Leukemia multidrug resistance associated protein,Malignant transformation suppression 1 （MTS1）,Malignant transformation suppression 1,Metastasin,MTS1,OTTHUMP00000015467,OTTHUMP00000015468,P9KA,PEL98,Placental calcium-binding protein,Protein Mts1,Protein S100 A4,Protein S100-A4,S100 calcium binding protein A4 （calcium protein,calvasculin,metastasin,murine placental homolog）,S100 calcium binding protein A4,S100 calcium-binding protein A4,S100a4,S10A4
Host：Mouse
Reactivity：Human
Applications：IHC-p
Concentration：1mg/mL
Immunogen：Full length protein from eukaryotic expression system.
Purification Method：Affinity purification
Clonality：Monoclonal
Clone No.：LE0231
Conjugation：Unconjugated
Buffer：PBS with 50％ glycerol, 0.5％ BSA and 0.02％ sodium azide.
Dilution：IHC 1：100-1：200
Swissprot：P26447
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Signal transduction
