Background:Mismatch repair gene hMLH1 is a ubiquitous gene encoding the mismatch repair protein (MMR) known as MutL protein homolog 1 (MLH1). MLH1 is utilized by normal proliferating cells to repair point mutations that may occur during DNA replication. Antibodies to MLH1 are a useful aid for classification of colorectal cancer.
仕様
Synonyms:COCA 2,COCA2,DNA mismatch repair protein Mlh1,FCC 2,FCC2,hMLH 1,hMLH1,HNPCC 2,HNPCC,HNPCC2,MGC5172,MLH 1,MLH1,MLH1,MutL homolog 1 (E. coli),MutL homolog 1,MutL homolog 1 colon cancer nonpolyposis type 2,MutL homolog 1,colon cancer,nonpolyposis type 2 (E. coli),MutL protein homolog 1,MutL,E. coli,homolog of,1
Host:Mouse
Reactivity:Human
Applications:IHC-p
Concentration:1mg/mL
Immunogen:Full length protein from eukaryotic expression system.
Purification Method:Affinity purification
Clonality:Monoclonal
Clone No.:LE0168
Conjugation:Unconjugated
Buffer:PBS with 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution:IHC 1:100-1:200
Swissprot:P40692
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling