Background：FLI1 is a transcription factor containing an ETS DNA-binding domain. It can translocate with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated translocation involving this gene has also been identified. Diseases associated with FLI1 includeIsolated Delta-Storage Pool DiseaseandEwing Sarcoma. Among its related pathways areTranscriptional misregulation in cancerandNF-kappaB Signaling.
仕様
Synonyms：ERGB transcription factor,Ewing Sarcoma breakpoint region 2,EWSR 2,EWSR2,FLI 1,FLI 1 proto oncogene,Fli-1 proto-oncogene,ETS transcription factor,FLI1,FLI1 EWS fusion gene,FLI1 proto oncogene,FLI1,Friend leukemia integration 1 （FLI1） transcription factor,Friend leukemia integration 1 transcription factor,Friend leukemia virus integration 1,Proto-oncogene Fli-1,Sarcoma breakpoint region 2 （EWSR2）,SIC 1,SIC1,Transcription factor ERGB,Viral integration region FLI1,Viral integration region FLI1,mouse,homolog of
Host：Mouse
Reactivity：Human
Applications：IHC-p
Concentration：1mg/mL
Immunogen：Full length protein from eukaryotic expression system.
Purification Method：Affinity purification
Clonality：Monoclonal
Clone No.：LE8A1
Conjugation：Unconjugated
Buffer：PBS with 50％ glycerol, 0.5％ BSA and 0.02％ sodium azide.
Dilution：IHC 1：100-1：200
Swissprot：Q01543
Isotype：IgG
Research Areas：Cancer, Cell biology, Epigenetics and Nuclear Signaling, Metabolism
