Background： ICAM-1 （intercellular adhesion molecule-1） is a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM-1 is expressed mainly on monocytes and endothelial cells, but expression can be induced or upregulated on many cell types including B and T lymphocytes. Diseases associated with ICAM1 includeMalariaandLeukostasis. Among its related pathways areImmune response CCR3 signaling in eosinophilsandImmunoregulatory interactions between a Lymphoid and a non-Lymphoid cell.
仕様
Synonyms：Antigen identified by monoclonal BB2,BB 2,BB2,CD 54,CD_antigen=CD54,CD54,Cell surface glycoprotein P3.58,Human rhinovirus receptor,ICAM 1,ICAM-1,ICAM1,ICAM1,intercellular adhesion molecule 1 （CD54）,human rhinovirus receptor,Intercellular adhesion molecule 1,Major group rhinovirus receptor,MALA 2,MALA2,MyD 10,MyD10,P3.58,Surface antigen of activated B cells,BB2
Host：Mouse
Reactivity：Human
Applications：IHC-p
Concentration：1mg/mL
Immunogen：Full length protein from eukaryotic expression system.
Purification Method：Affinity purification
Clonality：Monoclonal
Clone No.：LE0050
Conjugation：Unconjugated
Buffer：PBS with 50％ glycerol, 0.5％ BSA and 0.02％ sodium azide.
Dilution：IHC 1：100-1：200
Swissprot：P05362
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Immunology, Stem cells
