Background：CD45,also known as leukocyte common antigen （LCA）,B220,and T200,is a 180-240 kD single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells,except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth,differentiation,cell cycle,and oncogenic transformation. CD45 is one of the best negative selection markers for characterizing and/or isolating human mesenchymal stem cells from bone marrow and other sources. Along with the positive selection markers （such as CD29,CD44,CD90,CD105 and CD166）,negative selection markers （such as CD34 and CD45） are used for MSC identification.
仕様
Synonyms：B220,CD 45,CD45,CD45 antigen,CD45R,GP180,L-CA,LCA,Leukocyte common antigen,loc,Ly-5,LY5,Ly5,homolog of,Lyt-4,OTTHUMP00000033813,OTTHUMP00000033816,OTTHUMP00000033817,OTTHUMP00000038574,Protein tyrosine phosphatase receptor type c polypeptide,Protein tyrosine phosphatase,receptor type C,protein tyrosine phosphatase,receptor type,C,Protein tyrosine phosphatase,receptor type,c polypeptide,Ptprc,PTPRC,Receptor-type tyrosine-protein phosphatase C,T200,T200 glycoprotein,T200 leukocyte common antigen
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1.15 mg/mL
Immunogen：Recombinant protein corresponding to Mouse Human CD45.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：WB 1：500-1：1000
Swissprot：P08575,P06800
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Immunology, Neuroscience, Signal transduction, Stem cells
