Background：The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
仕様
Synonyms：zgc：100779,BMP 2B,BMP 4,BMP-2B,BMP-4,BMP2B,BMP2B1,BMP4,BMP4,Bone morphogenetic protein 2B,Bone morphogenetic protein 4,DVR4,MCOPS6,MGC100779,OFC11,zbmp-4,ZYME
Host：Rabbit
Reactivity：Mouse
Applications：IHC
Concentration：1.9 mg/mL
Immunogen：Recombinant protein corresponding to Mouse Mouse BMP4.
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：IHC 1：1000-1：2000
Swissprot：P21275, Q06826
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Developmental biology, Signal transduction, Stem cells
