Background：This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 （MCP-2）, macrophage inflammatory protein 1 alpha （MIP-1 alpha）, macrophage inflammatory protein 1 beta （MIP-1 beta） and regulated on activation normal T expressed and secreted protein （RANTES）. Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation.
仕様
Synonyms：AM4 7,C C chemokine receptor type 5,C C CKR 5,C-C chemokine receptor type 5,C-C CKR-5,C-C motif chemokine receptor 5 A159A,CC Chemokine Receptor 5,CC Chemokine Receptor Type 5,CC CKR 5,CC-CKR-5,CCCKR 5,CCCKR5,CCR 5,CCR-5,CCR5,CCR5 chemokine （C C motif） receptor 5,CCR5,CD 195,CD195,CD195 Antigen,Chemokine C C motif receptor 5,Chemokine receptor CCR5,CHEMR13,CKR 5,CKR5,CMKBR 5,CMKBR5,FLJ78003,HIV 1 Fusion Coreceptor,HIV-1 fusion coreceptor,HIV1 fusion coreceptor,IDDM22,MIP-1 alpha receptor
Host：Rabbit
Reactivity：Mouse,Rat
Applications：IHC
Concentration：0.55 mg/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse CCR5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：IHC 1：500-1：1000
Swissprot：P51682,O08556
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Immunology, Microbiology, Neuroscience, Signal transduction
