Background：This gene encodes a member of the peroxisome proliferator-activated receptor （PPAR） subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors （RXRs） and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known： PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
仕様
Synonyms：CIMT1,GLM1,NR1C3,Nuclear receptor subfamily 1 group C member 3,OTTHUMP00000185032,OTTHUMP00000185036,Peroxisome proliferator activated nuclear receptor gamma variant 1,Peroxisome proliferator activated receptor gamma 1,Peroxisome Proliferator Activated Receptor gamma,Peroxisome proliferator-activated receptor gamma,PPAR gamma,PPAR-gamma,PPARG,PPARG,PPARG1,PPARG2,PPARgamma
Host：Mouse
Reactivity：Mouse,Rat
Applications：IHC
Concentration：1.1 mg/mL
Immunogen：Recombinant protein corresponding to Mouse PPARgamma
Purification Method：Affinity purification
Clonality：Monoclonal
Clone No.：6D7B9
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：IHC 1：500-1：2000
Swissprot：P37238,O88275
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience, Stem cells
