Background：Bone morphogenetic protein-2 （BMP-2） is a member of the transforming growth factor-beta （TGFB） superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer,which binds to its receptor. There is also a 40-45 kDa form of BMP2,as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway,TGF beta signaling pathway,and cytokine-cytokine receptor interaction.
仕様
Synonyms：BDA2,BMP-2,BMP-2A,Bmp2,BMP2,BMP2A,Bone morphogenetic protein 2,Bone morphogenetic protein 2A
Host：Mouse
Reactivity：Rat
Applications：IHC
Concentration：2.65 mg/mL
Immunogen：Recombinant protein corresponding to Mouse BMP2
Purification Method：Affinity purification
Clonality：Monoclonal
Clone No.：2H6D12
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：IHC 1：500-1：1000
Swissprot：P12643,P21274,P49001
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Signal transduction, Stem cells
