Background：Caveolin-1 （CAV1）,a multifunctional protein,is the main constituent molecule of caveolae and represents a scaffolding molecule for several signaling molecules including epidermal growth factor receptor . Several studies have implicated that a reduced expression of CAV1 was found in cancers including head and neck carcinoma . However,other studies recognize CAV1 as a tumor promoter because CAV1 is overexpressed in various kinds of cancers,especially in oral cancer . Recent study also show that CAV1 is involved in astric Cancer .
仕様
Synonyms：BSCL3,CAV,CAV1,CAV1,caveolae protein,22 kD,caveolin 1 alpha isoform,caveolin 1 beta isoform,Caveolin 1 caveolae protein 22kDa,Caveolin-1,Caveolin1,cell growth-inhibiting protein 32,CGL3,LCCNS,MSTP085,OTTHUMP00000025031,PPH3,VIP 21,VIP21
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：0.9 mg/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse Caveolin-1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：WB 1：800-1：1000, IHC 1：1000-1：3000
Swissprot：Q03135,P49817,P41350
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction, Tags ＆ Cell Markers
