Background：The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signaling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
仕様
Synonyms：GCG,GLP 2,GLP1,GLP2,glucagon,GRPP,Glucagon like peptide 1,GRPP Oxyntomodulin,OXM,Proglucagon
Host：Rabbit
Reactivity：Mouse,Rat
Applications：IHC,IF
Concentration：1 mg/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse Glucagon
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：IHC 1：500-1：1000, IF 1：200-1：500
Swissprot：P55095,P06883
Isotype：IgG
Research Areas：Cancer, Metabolism, Developmental biology, Signal transduction, Stem cells
