Background：The protein encoded by this gene is a member of the scavenger receptor cysteine-rich （SRCR） superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仕様
Synonyms：C163A,CD 163,CD163,CD163 antigen,CD163 molecule,Hemoglobin scavenger receptor,M130,M130 antigen precursor,Macrophage associated antigen,MM130,OTTHUMP00000238617,OTTHUMP00000238618,OTTHUMP00000238619,OTTHUMP00000238620,SCARI1,Scavenger receptor cysteine rich type 1 protein M130,sCD163,Soluble CD163
Host：Rabbit
Reactivity：Mouse,Rat
Applications：IHC
Concentration：340 ug/mL
Immunogen：Recombinant protein corresponding to Mouse CD163
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
