Background:This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:DCR,DCR1,Dicer 1 ribonuclease III,Dicer 1 ribonuclease type III,Dicer,DICER,DICER1,Double-strand-specific ribonuclease,Endoribonuclease Dicer,Helicase MOI,Helicase with RNase motif,HERNA,KIAA0928,MNG1,RMSE2
Host:Rabbit
Reactivity:Human,Rat
Applications:IHC
Concentration:1 mg/mL
Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse Dicer
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide,100 ug/ml BSA and 50% glycerol.
Dilution:IHC 1:1000
Swissprot:Q9UPY3,Q8R418
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling