Background：S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs and has been implicated in the regulation of cellular activities such as metabolism, motility and proliferation. In the nervous system, S100B is constitutively released by astrocytes into the extracellular space and at nanomolar concentrations, it can promote neurite outgrowth and protect neurons against oxidative stress. Within the central nervous system （CNS）, S100B is thought to be a marker for astroglial activation, linking astrocyte dysfunction to schizophrenia. In addition to astrocytes, S100B is released from many cell types, such as, adipocytes, chondrocytes, cardiomyocytes and lymphocytes. Serum S100B represents a new boimarker for mood disorders.
仕様
Synonyms：NEF,Protein S100 B,Protein S100-B,S 100 calcium binding protein beta chain,S 100 protein beta chain,S-100 protein beta chain,S-100 protein subunit beta,S100,S100 calcium binding protein beta （neural）,S100 calcium-binding protein B,S100 protein beta chain,S100B,S100B,S100beta
Host：Rabbit
Reactivity：Mouse,Rat
Applications：IHC
Concentration：0.54 mg/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse S100B
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：IHC 1：500-1：1000
Swissprot：P50114,P04631
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Stem cells
