Background：ATG7 （Autophagy Related 7） is a Protein Coding gene. Among its related pathways are Autophagy Pathway and Innate Immune System. GO annotations related to this gene include protein homodimerization activity and ubiquitin activating enzyme activity. This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：1810013K23Rik,Apg 7,APG7 autophagy 7 like,APG7 autophagy 7-like （S. cerevisiae）,APG7 like,APG7,S. cerevisiae,homolog of,APG7-like,APG7L,ATG 7,ATG12-activating enzyme E1 ATG7,ATG7,ATG7 autophagy related 7 homolog （S. cerevisiae）,ATG7 autophagy related 7 homolog,ATG7,Atg7l,Autophagy 7,S. cerevisiae,homolog of,Autophagy related protein 7,Autophagy-related 7 （yeast）,Autophagy-related protein 7,DKFZp434N0735,GSA 7,GSA7,hAGP7,Ubiquitin activating enzyme E1 like protein,Ubiquitin-activating enzyme E1-like protein,Ubiquitin-like modifier-activating enzyme ATG7
Host：Rabbit
Reactivity：Mouse
Applications：IHC
Concentration：0.6 mg/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to mouse ATG7
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：IHC 1：600-1：1200
Swissprot：Q9D906,O95352
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Metabolism, Signal transduction
