Background：CDK1, also named as CDC2, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily.CDC2 plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. CDC2 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor （MPF）, which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. It is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II. Mitotic cyclins stably associate with CDC2 and function as regulatory subunits. The antibody is specific to the 2 isoforms of CDC2.
仕様
Synonyms：Cdc 2,Cdc2,CDC28A,CDK 1,CDK1,CDK1,CDKN1,CELL CYCLE CONTROLLER CDC2,Cell division control protein 2,Cell division control protein 2 homolog,Cell division cycle 2 G1 to S and G2 to M,Cell division protein kinase 1,Cell Divsion Cycle 2 Protein,Cyclin Dependent Kinase 1,Cyclin-dependent kinase 1,DKFZp686L20222,MGC111195,p34 Cdk1,p34 protein kinase,P34CDC2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：2.5 mg/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to mouse CDK1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：WB 1：500-1：1000
Swissprot：P06493,P11440,P39951
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Neuroscience
