Background：Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones （H2A, H2B, H3, and H4） form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
仕様
Synonyms：H2A histone family member X,H2A histone family member X,H2A.FX,H2A.X,H2a/x,H2AFX,H2AX,H2AX,Histone H2A.X
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：0.86 mg/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse Histone H2A.X
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：WB 1：1000, IHC 1：500-1：1500
Swissprot：P16104,P27661
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
