Background：TLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide （LPS）. TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
仕様
Synonyms：ARMD10,CD284,CD284 antigen,Homolog of Drosophila toll,hToll,TLR 4,TLR4,TLR4,TOLL,Toll like receptor 4,Toll-like receptor 4
Host：Mouse
Reactivity：Mouse,Rat
Applications：IHC
Concentration：1.8 mg/mL
Immunogen：Recombinant protein corresponding to Mouse TLR4
Purification Method：Affinity purification
Clonality：Monoclonal
Clone No.：2E12C8
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：IHC 1：500-1：1000
Swissprot：Q9QUK6,Q9QX05
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Immunology, Microbiology
