Background：This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
仕様
Synonyms：NAD dependent deacetylase sirtuin 7,NAD dependent protein deacetylase sirtuin 7,NAD-dependent protein deacetylase sirtuin-7,Regulatory protein SIR2 homolog 7,Silent mating type information regulation 2 homolog,Silent mating type information regulation 2 S.cerevisiae homolog 7,SIR2 L7,SIR2 like protein 7,Sir2 related protein type 7,SIR2,S.CEREVISIAE,HOMOLOG-LIKE 7,SIR2-like protein 7,SIR2L 7,SIR2L7,SIR7,SIRT 7,SIRT7,Sirtuin 7,Sirtuin type 7,Sirtuin7
Host：Rabbit
Reactivity：Human
Applications：IHC
Concentration：190 ug/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse SIRT7
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：IHC 1：200-1：400
Swissprot：Q9NRC8,Q8BKJ9
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism
