Background：NR1H3,also known as LXRA,is a liver X receptors,which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function,controlling transcriptional programs involved in lipid homeostasis and inflammation.. It's also a ligand-activated LXRs and forms heterodimers with retinoid X receptor,then participates in regulating expression of target genes containing LXR response elements.
仕様
Synonyms：Liver X receptor alpha,LXR a,LXRA,NR1H3,NR1H3,Nuclear receptor subfamily 1 group H member 3,Oxysterols receptor LXR alpha,Oxysterols receptor LXR-alpha,RLD 1,RLD1
Host：Rabbit
Reactivity：Mouse,Rat
Applications：IHC
Concentration：0.53 mg/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse LXRa
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：IHC 1：1000-1：2006
Swissprot：Q9Z0Y9,Q62685
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction
