Background：This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
仕様
Synonyms：Alpha 1 type II collagen,Alpha-1 type II collagen,AOM,Cartilage collagen,Chondrocalcin,CO2A1,COL11A3,Col2a1,Collagen II alpha 1 polypeptide,SEDC
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,IF
Concentration：230 ug/mL
Immunogen：Recombinant protein corresponding to Mouse COL2A1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：WB 1：500-1：2000, IHC 1：100-1：500, IF 1：100-1：500
Swissprot：P02458,P28481,P05539
Isotype：IgG
Research Areas：Cancer, Signal transduction, Stem cells
