Background：This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
仕様
Synonyms：C C chemokine receptor type 2,C C CKR 2,C-C chemokine receptor type 2,C-C CKR-2,CC chemokine receptor type 2,CC CKR 2,CC-CKR-2,CCCKR2,CCR 2,CCR-2,CCR1L,CCR2,CCR2,CCR2A,CCR2B,CCR5L,CD192,CD192 antigen,Chemokine C C motif receptor 2,Chemokine CC Motif Receptor 2,CKR 2,CKR2,CKR2A,CKR2B,CMKBR2,MCP 1 R,MCP-1-R,MCP1 RECEPTOR,MCP1R,Monocyte chemoattractant protein 1 receptor,Monocyte Chemotactic Protein 1 Receptor,Monocyte Chemotactic Protein 1 Receptor
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC
Concentration：1.35 mg/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse CCR2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：IHC 1：800-1：3000
Swissprot：P41597,P51683,O55193
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Immunology, Microbiology, Signal transduction
