Background:This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
仕様
Synonyms:JAK 2,JAK-2,JAK2,JAK2,Janus Activating Kinase 2,Janus kinase 2 (a protein tyrosine kinase),Janus kinase 2,JTK 10,JTK10,kinase Jak2,OTTHUMP00000043260,THCYT3,Tyrosine protein kinase JAK2,Tyrosine-protein kinase JAK2
Host:Rabbit
Reactivity:Mouse,Rat
Applications:WB
Concentration:1 mg/mL
Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse JAK2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide,100 ug/ml BSA and 50% glycerol.
Dilution:WB 1:500-1:1000
Swissprot:Q62120,Q62689
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal transduction