Background：This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element （CRE）, an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase （HAT） that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene.
仕様
Synonyms：Activating transcription factor 2,Activating transcription factor 2 splice variant ATF2 var2,ATF 2,Atf-2,Atf2,ATF2 protein,ATF2,cAMP Response Element Binding Protein 2,cAMP response element binding protein CRE BP1,cAMP response element-binding protein CRE-BP1,cAMP responsive element binding protein 2,formerly,cAMP-dependent transcription factor ATF-2,cAMP-responsive element-binding protein 2,CRE BP1,CRE-BP,CREB 2,CREB-2,CREB2,CREBP1,Cyclic AMP dependent transcription factor ATF 2,Cyclic AMP-dependent transcription factor ATF-2,Cyclic AMP-responsive element-binding protein 2,D130078H02Rik,D18875,HB 16,HB16,Histone acetyltransferase ATF2,MGC105211,MGC105222,MGC111558,MGC142504,mXBP,MXBP protein,Tg（Gzma-Klra1）7Wum,TREB 7,TREB7
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC
Concentration：490 ug/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse ATF2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：IHC 1：500-1：1000
Swissprot：P15336,P16951,Q00969
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Immunology
