Background：The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
仕様
Synonyms：antigen identified by monoclonal L230,CD 51,CD51,DKFZp686A08142,Integrin alpha five,integrin alpha V beta 3,Integrin alpha-5,integrin alpha-V,Integrin alpha-V light chain,integrin alphaVbeta3,integrin,alpha V （vitronectin receptor,alpha polypeptide,antigen CD51）,ITAV,ITGAV,MSK 8,Msk8,Vitronectin receptor subunit alpha,VNRA,VTNR
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：0.76 mg/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse Integrin alpha-V
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：WB 1：500-1：1000
Swissprot：P06756,P43406
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Microbiology, Stem cells
