Background：This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
仕様
Synonyms：chuk,CHUK1,Conserved Helix Loop Helix Ubiquitous Kinase,Conserved helix loop ubiquitous kinase,Conserved helix-loop-helix ubiquitous kinase,I Kappa B Kinase 1,I Kappa B Kinase Alpha,I-kappa-B kinase 1,I-kappa-B kinase alpha,IkappaB kinase,IkB kinase alpha subunit,IkBKA,IKK 1,IKK A,IKK a kinase,IKK-A,IKK-alpha,IKK1,IKKA,IKKA,Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B Cells,Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit,Inhibitor of nuclear factor kappa-B kinase subunit alpha,NFKBIKA,Nuclear Factor Kappa B Inhibitor Kinase Alpha,Nuclear factor NF kappa B inhibitor kinase alpha,Nuclear factor NF-kappa-B inhibitor kinase alpha,Nuclear factor NFkappaB inhibitor kinase alpha,Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells Inhibitor,TCF-16,TCF16,Transcription factor 16
Host：Rabbit
Reactivity：Human
Applications：IHC
Concentration：0.57 mg/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse IKKa
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：IHC 1：200-1：600
Swissprot：O15111,Q60680
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Immunology, Signal transduction
