Background:The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
仕様
Synonyms:campomelic dysplasia autosomal sex reversal,CMD 1,CMD1,CMPD 1,CMPD1,SOX 9,Sox9,SOX9,SRA 1,SRA1,SRXX2,SRXY10,SRY (sex determining region Y) box 9 (campomelic dysplasia autosomal,SRY (sex determining region Y) box 9,SRY (sex determining region Y)-box 9,SRY (sex-determining region Y)-box 9 protein,SRY related HMG box gene 9,Transcription factor SOX 9,Transcription factor SOX-9,transcription factor SOX9
Host:Rabbit
Reactivity:Mouse,Rat
Applications:WB
Concentration:0.6 mg/mL
Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse SOX9
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide,100 ug/ml BSA and 50% glycerol.
Dilution:WB 1:500-1:1000
Swissprot:Q04887
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Neuroscience, Stem cells