Background:This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
仕様
Synonyms:Active transcription factor CREB,cAMP response element binding protein 1,cAMP response element binding protein,cAMP responsive element binding protein 1,cAMP-responsive element-binding protein 1,CREB,CREB-1,CREB1,CREB1,Cyclic AMP-responsive element-binding protein 1,MGC9284,OTTHUMP00000163864,OTTHUMP00000163865,OTTHUMP00000206660,OTTHUMP00000206662,OTTHUMP00000206667,Transactivator protein
Host:Rabbit
Reactivity:Human
Applications:IHC
Concentration:400 ug/mL
Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse CREB1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.02% sodium azide,100 ug/ml BSA and 50% glycerol.
Dilution:IHC 1:200-1:800
Swissprot:P16220,Q01147,P15337
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Immunology