Background：This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.
仕様
Synonyms：Connexin 43,Connexin-43,Cx 43,Cx43,CXA1,DFNB38,Gap junction 43 kDa heart protein,Gap junction alpha-1 protein,Gap junction protein alpha 1 43kDa （connexin 43）,Gap junction protein alpha 1 43kDa,Gap junction protein alpha like,GJA 1,Gja1,GJAL,ODD,ODDD,ODOD,SDTY3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：0.53 mg/mL
Immunogen：KLH conjugated Synthetic peptide corresponding to Mouse Connexin 43
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.02％ sodium azide,100 ug/ml BSA and 50％ glycerol.
Dilution：WB 1：1000-1：5000, IHC 1：100-1：500
Swissprot：P17302,P23242,P08050
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Signal transduction
